Bedaquiline Dose-PK-Efficacy-Safety-Outcome Simulation Framework

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Record description

Title: Bedaquiline Dose-PK-Efficacy-Safety-Outcome Simulation Framework
DOI: https://doi.org/10.82595/scilifelab.qkfp9-m7094
Description: This Shiny interactive simulation tool is aimed for interested users to visualize and explore different dosing strategies of bedaquiline in an integrated pharmacokinetic, pharmacodynamic and long-term outcome modelling framework using patient characteristics, concomitant medications in flexible simulation settings. Users can also simulate individual time-to-positivity (TTP) data with the desired number of subjects and planned sampling timepoints, which enables further data analysis.
URL: https://bedaquiline-dose-pk-pd-outcome.serve.scilifelab.se
Source code: https://github.com/slove1200/BDQ-simulation-framework-shiny
Docker image: docker.io/yujou1200/bedaquiline-dose-pk-pd-outcome:20260525-110236
Date submitted: 2025-02-27 15:22
Date updated: 2026-08-11 11:08
Date available: 2026-08-11 11:08
Language: English

Journal article: 10.1002/psp4.70264

Version 1:
https://doi.org/10.82595/scilifelab.qkfp9-m7094 current

To cite all versions, use the following DOI:
https://doi.org/10.82595/scilifelab.td2fp-0g809