Chalmers University of Technology
Fraunhofer Institute for Translational Medicine and Pharmacology
Göteborgs University
KTH Royal Institute of Technology
Karolinska Institutet
Karolinska institutet
LTH Lund University
Linköping University
Lund University
SciLifeLab
Stockholm University
Swedish Meteorological and Hydrological Institute
Swedish University of Agricultural Sciences
Umeå University
University of Helsinki
Uppsala University
starbase is a web-based application that provides various analytical and visualization tools for exploring large eukaryotic transposable elements known as Starships.
Librarian is an open-access, web-based application for building and sharing high-quality MS² spectral libraries for nontarget high-resolution mass spectrometry. It provides a streamlined, end-to-end workflow to retrieve and harmonize chemical metadata from PubChem, design compound mixtures for HRMS acquisition, and assemble standardized, metadata- ... See more
IFCB Plankton Classifier is a web application that automates phytoplankton image classification using a ResNet-50 model trained on the SMHI IFCB Plankton Image Reference Library and NIVA datasets. It combines single-image inference, large-scale batch processing, and threshold-aware prediction visualisation to streamline marine plankton analysis wo ... See more
A frontface to EU-OpenScreen Impulse
Given either: a nucleotide FASTA (genome/transcriptome), or a precomputed protein FASTA, and a table of epitope peptide sequences, the tool: Optionally generates a 6-frame translation (3 forward + 3 reverse-complement frames). Scans translated/protein sequences for exact epitope matches. Writes hit tables for downst ... See more
OlinkWrapper provides a user-friendly interface for performing quick analysis of Olink data using OlinkAnalyze package. It allows for data upload, parameter customization, visualization of results, and exporting of analysis outputs.
AI Agent that autonomously plans and executes data-driven workflows related to Drug Repurposing. It combines autonomous research, data extraction, knowledge graph construction, and analytical reasoning, featuring a long-term memory that enhances the system over time.
LymphMutSig is an interactive platform that provides a comprehensive atlas of mutational signatures in B-cell cancers and enables user-driven mutational signature analysis of B-cell cancer genomic data.
5PSeq is a method for profiling 5' phosphorylated mRNA undergoing decay. Degradation coincides with translation, as the enzymatic cleavage of the 5' end of mRNAs occurs right behind the last trailing ribosome. Therefore, information about ribosome dynamics can be obtained by profiling the degradome (5PSeq). 5PSeq Explorer is a web application tha ... See more
Tools for normalization, evaluation of outliers, technical biases and batch effects and differential expression analysis.
Chromatin interaction database for b-cell precursor acute lymphoblastic leukemia
Build leakage-free Drug-Target Affinity datasets from ChEMBL and train Graph Neural Networks for target-specific binding affinity prediction
PKSmart is an open-source app framework built specifically for predicting human and animal PK parameters
DICTrank Predictor is an open-source app framework built specifically for human drug-induced cardiotoxicity (DICT).DICTrank Predictor employs physicochemical parameters as feature. For more details look at https://www.biorxiv.org/content/10.1101/2023.10.15.562398v1
DILI Predictor is an open-source app framework built specifically for human drug-induced liver injury (DILI). DILI Predictor employs eleven proxy-DILI labels from in vitro and in vivo datasets along with pharmacokinetic parameters, structural fingerprints and physicochemical parameters as features.
KG Generator app under KGG in Data Science Toolkit
A resource of validated and annotated gene fusions in cancer cell lines
Dashboard for the R4A Expertise KG
Fallback app of datascience toolkit
This is an interactive Shiny-based app that visualises the analysed data for CRISPR screens using the PbHiT system in the rodent malaria parasite Plasmodium berghei as described in Jonsdottir et al. 2024 generated by the Bushell lab (www.bushelllab.com/) at Umeå University
A shiny application to process OLINK data. Outlier detection - filtering - statistical analysis - visualization - publication ready figures all at one place.
gsalit is a user-friendly Streamlit application that allows researchers to run the Illumina GSA (Global Screening Array) genotyping pipeline without manually handling command-line tools. A second version, built with Python and Conda, and available via Bioconda.
This application: XPS Files: Converts XPS to PDF using xpstopdf (requires libgxps-utils) PDF Files: Extracts tables using advanced table detection Number Format: Handles Swedish format (comma as decimal separator) Table Merging: Automatically merges fragmented tables from multiple pages Excel Export: Saves each file's tables to separate Exc ... See more
ThermoTargetMiner is an interactive Shiny application that enables simplified visualization and exploration of drug–target relationships derived from the Proteome Integral Solubility Alteration (PISA) assay. The app integrates processed data from 67 approved drugs and candidate compounds tested in lung cancer cell lines, providing users with tools ... See more
HDAnalyzeR-app is a graphical interface for HDAnalyzeR R-package developed by the Human Disease Blood Atlas. The goal is to simplify data analysis for biomarker discovery in disease research. With HDAnalyzeR, you can easily perform tasks like protein differential expression analysis, classification modeling, dimensionality reduction and data visua ... See more
lipidomics
Data browser showing peptide-level mass spectrometry proteome associations with affinity proteomics
A single shiny solution from sequencer data to pathway analysis
CitizenScience Project
Related publication: Andersson, Axel, et al. "Points2Regions: Fast, interactive clustering of imaging‐based spatial transcriptomics data." Cytometry Part A 105.9 (2024): 677-687. https://doi.org/10.1002/cyto.a.24884
Predicts Ames Mutagenicity for a chemical structure using an SVM model with Signatures features via the CPSign modeling tool.
It helps to calculate sequencing depth required to get microbial genomes from metagenomics
The Multifunctional Potential and Cost Matrix provides an integrated assessment of the benefits and costs of urban blue-green infrastructure (BGI) elements. Firstly, the potential to provide three functions: urban stormwater management, heat stress reduction and recreation, is assessed based on scientific evidence. Secondly, the combined performan ... See more
CAPIM is an integrative computational pipeline for identifying and characterizing catalytic sites in proteins. It combines enzymatic activity prediction, pocket detection, and ligand docking simulations to determine active residues and annotate them with Enzyme Commission (EC) numbers computationally. CAPIM supports multi-chain protein structures, ... See more
enrichedmassspec - a shiny app to visualize differentially expressed proteins (DEPs) and carry out enrichment analysis using different methods on Mass Spectrometry data from generated using spectronaut
This app provides a reference database of proteins found in dried blood spots, based on published scientific studies. It serves as a tool for exploring the dried blood spot proteome.
This app provides complementary visualizations of affinity proteomics data generated from dried blood spot (DBS) samples collected from a mouse model. The visualizations present longitudinal protein profiles in infected and uninfected mice, heatmaps of protein-protein correlations, and data quality assessments.
Suite of data science tools made by Fraunhofer ITMP
Drug Likeness Assessment app under KGG in Data Science Toolkit
KG Visualizer app under KGG in Data Science Toolkit
peak cluster
KISSE is a species search engine that utilizes collagen sequences from eight different species to identify unknown samples.
The Chemical Biology Atlas (https://doi.org/10.1101/2025.07.23.666341) is an interactive online platform designed to facilitate the exploration of biological activities, mechanisms of action, and molecular targets associated with chemical compounds. Built on a Neo4j graph database, the Atlas enables intuitive navigation of complex relationships be ... See more
New interventions to control malaria depend on a deep understanding of the parasite that causes the disease. The PlasmoGEM project produces free genetic tools for research on malaria parasites. We also use the reagents in genetic screens to identify parasite gene functions at scale. The purpose of this database is to share data generated by the p ... See more
An app designed to explore the *Populus* transcriptome throughout a yearly growth cycle. POPUL-R is based on a RNA-Seq dataset we have obtained from different poplar tissues in outdoor and indoor conditions, published in Marcon et. al (2025). In this app, you can perform exploratory analyses on your genes of interest such as visualizing their exp ... See more
Biome-specific gene catalogues have been recovered for many environments using shotgun metagenomics, followed by assembly and gene calling on the assembled contigs. We recently proposed a novel mix-assembly strategy, combining individual and co-assembly approaches, and used this approach to assemble an extensive non-redundant gene set from 124 Bal ... See more
This site provides a databases of knockout designs targeting the entire Plasmodium berghei protein encoding genome using the PbHiT CRISPR system as described in Jonsdottir et al. DOI: https://doi.org/10.1101/2024.04.20.590404
Predicting chemical EC50 and EC10 ecotoxiticy values towards fish, aquatic invertebrate, and algae for a diverse set of effects using AI. Publication in Science Advances available through DOI: https://doi.org/10.1126/sciadv.adk6669
This predictive model distinguishes between Relapsing-Remitting Multiple Sclerosis (RRMS) and Secondary Progressive Multiple Sclerosis (SPMS) using electronic health records collected at each hospital visit, with a focus on identifying transitions from RRMS to SPMS. It incorporates Conformal Prediction (CP) to quantify uncertainty and integrates E ... See more
**SNRApp** is an interactive web app to calculate the Signal-to-Noise Ratio (SNR) from spatial omics data. The user will need to upload an `anndata` and set the top and bottom percentile.
Apical hook kinetics analyzer: Shiny app to quantify and visualize kinematics based on angle measurements of Arabidopsis thaliana dark-grown seedlings extracted from time-series.
TurgoLab is an interactive, FEM-based simulation app for inflating 2D cellular structures from .geo files. It integrates the BVPy framework to enable intuitive biomechanical modeling of plant tissues under turgor pressure from the geometry made with Anatomeshr .
TissUUmaps demo
A converter of 2D plant anatomical data into finite element mesh (GEO) format.
Visualizations of the results from an interaction screen of 215 G protein-coupled receptors (GPCRs) and the receptor activity–modifying proteins (RAMPs). Companion app to ‘Multiplexed mapping of the interactome of GPCRs with receptor activity–modifying proteins’, https://doi.org/10.1126/sciadv.ado9959
Visualizations of the results from a selectivity screen of >400 antibodies targeting 215 G protein-coupled receptors (GPCRs). Companion app to ‘Multiplexed selectivity screening of anti-GPCR antibodies’, https://doi.org/10.1126/sciadv.adf9297
ShinyCell app detailing cellular landscape of equine asthma
Hosting page for AntiMicRobial KG and prediction models.
Supplementary material to Sdougkou et al. 2024, "Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood" Environmental Science & Technology, 58 (37) 16302–16315 https://doi.org/10.1021/acs.est.4c05235
Related publication: Li, Xiaofei, et al. "Profiling spatiotemporal gene expression of the developing human spinal cord and implications for ependymoma origin." Nature neuroscience 26.5 (2023): 891-901. https://doi.org/10.1038/s41593-023-01312-9
Related publication: Kukanja, Petra, et al. "Cellular architecture of evolving neuroinflammatory lesions and multiple sclerosis pathology." Cell 187.8 (2024): 1990-2009. https://doi.org/10.1016/j.cell.2024.02.030
Related publication: Andersson, Axel, et al. "Cell segmentation of in situ transcriptomics data using signed graph partitioning." International Workshop on Graph-Based Representations in Pattern Recognition. Cham: Springer Nature Switzerland, 2023. https://doi.org/10.1007/978-3-031-42795-4_13
Related publication: Ström, Peter, et al. "Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study." The Lancet Oncology 21.2 (2020): 222-232, https://doi.org/10.1016/S1470-2045(19)30738-7/
Explores interpretability for chest X-ray pathology predictions using methods—Grad-CAM, LIME, SHAP, and LRP. It provides heatmaps and evaluation metrics for better insights into the medical significance of predictions made by deep learning models.
This is for exploring blood phenotypes in plasmogem screen data.
This Shiny app provides a user-friendly interface for performing Weighted Gene Co-expression Network Analysis (WGCNA) on RNA-seq/Microarray and DNA methylation (Array/Sequencing) data. It allows for data upload, parameter customization, visualization of results, and exporting of analysis outputs.
MMAtt-DTA: MultiModal Attention Drug-Target Affinity prediction
Demo of Bayesian updating for teaching purposes. By Johan Henriksson, www.henlab.org. Source at https://github.com/henriksson-lab/demo_bayesupdate
Data exploration analysis tool. Load your csv data file and it will help to clean the data, report the missing/NA values (using pareto graph), perform a set of various statistical analyses (e.g., correlation, t-test, MW-test, KS-test, and more) resulting in tables and graphs.
Dashboard plotting the number of people in Sweden aged 0-19 who have have filled a prescription for ADHD medications each year.
Clusetering of phenotype data
Comparing 4 types of the most common reference populations for child sex- and age-adjusted Body Mass Index (BMI)
Service that provides a REST Api to convert between different chemical notations. More info: https://github.com/DouglasConnect/ChemIdConvert.
Allows users to either upload an image file or take a picture using their webcam and get a prediction the chemical structure depicted in the image in SMILES notation.
This app allows users to input an image (in jpeg format) of a flower and get a prediction on what type of flower it is from a machine learning model. Top three most likely flower types according to the model’s prediction are shown.
In-silico Drug Repurposing Catalogue REMEDi4ALL (iDRC-R4A).
API for Predicting Off-Target Binding Profiles With Confidence Using Conformal Prediction. Refer to https://doi.org/10.3389/fphar.2018.01256 for the paper describing the tool.
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IFNB single-cell transcriptomics data
Trancriptom analysis for Suprcellfactories project
scRNASeq of 55 samples from zebrafish brain. This project aims to characterize expression profile of different cell types.
The Mouse Organ Metabolite Atlas
Power analysis for RNA-Seq experiment. Estimate number of samples required and more.
Companion resource to the article, 'An online atlas of human plasma metabolite signatures of gut microbiome composition' by Dekkers et al
Meta-analysis of skeletal muscle response to exercise and inactivity
Single Protein Localization
Correlation Network
Heatmap
Network
Data Download
Application that allows users to get predictive data about compound (Multiple Molecules)
Application that allows users to get predictive data about compound (Single Molecule)
Imminent myocardial infarction prediction model. In patients free from prior cardiovascular disease, we aimed to identify characteristics of an imminent first heart attack and design a prediction model.
Shiny app for displaying Dictyostelium discoideum RNA-seq and proteomics data, from the publication Edelbroek et al. 2024
Model to predict the pKa of compounds
All the browsable datasets from Lee et al 2024. "Open source, high throughput, targeted in situ transcriptomics"
This dashboard visualises the spread of COVID-19 in Sweden: confirmed cases, ICU admissions, and deaths between February 2020 and March 2023.
Conformal regression model for predicting LogD for drug-like molecules, trained on ChEMBL version 33 with over 2.2M compounds using the CPSign software.
RepurposeDrugs - an interactive web-based data portal and predictive platform for repurposing mono- and combination therapies.
Modelling of cell-type signatures in the developmental human heart
Human heart development ISS datasets generated for Lazar et.al 2024.
Colorectal cancer usually metastasizes in the liver. Tumor cells can create two types of metastases: desmoplastic (DHGP) or replacement (RHGP). DHGP is characterized by a fibrotic rim that encapsulates the tumor cells and is associated with a better survival. In this project, we found two distinct areas in the rim: an outer area representing a ben ... See more
ALLIUM (ALL subtype Identification Using Machine learning) is a multimodal classifier of molecular subtypes in pediatric acute lymphoblastic leukemia, using DNA methylation (DNAm) and gene expression (GEX) data
Demo of ROC curves, PR curves, and decision boundaries for teaching purposes, www.henlab.org. By Johan Henriksson. Source at https://github.com/henriksson-lab/demo_roc
Demo of xgboost and decision trees for teaching purposes. By Johan Henriksson, www.henlab.org. Source at https://github.com/henriksson-lab/demo_xgboost
API for model that predicts water–octanol distribution coefficient (logD) for chemical compounds: It is a proxy for the lipophilicity which is a major determinant of drug properties and overall suitability of drug candidates
A Shiny webapp for creating a Seurat object without programming expertise. Load a count matrix directory, interactively filter on metadata, view results, download Seurat object and results of differential gene expression testing.
Demo of penalized linear models (elastic net) for teaching purposes. By Johan Henriksson, www.henlab.org. Source at https://github.com/henriksson-lab/demo_elasticnet
Demo of Bayesian linear models for teaching purposes. By Johan Henriksson, www.henlab.org. Source at https://github.com/henriksson-lab/demo_bayesianlinmod
Demo of markov chains and HMMs for teaching purposes. By Johan Henriksson, www.henlab.org. Source at https://github.com/henriksson-lab/demo_markovchain
Demo of the Poisson distribution, as relevant for NGS, for teaching purposes, www.henlab.org. By Johan Henriksson. Source at https://github.com/henriksson-lab/demo_poisson
Demo of statistical distributions for teaching purposes. By Johan Henriksson, www.henlab.org. Source at https://github.com/henriksson-lab/demo_statdist
Co-occurrence plots created using VOS viewer . There are three plots in total, each based on publications from a different SciLifeLab reporting group (i.e. affiliated researchers, infrastructure units, and SciLifeLab fellows). In each plot, we have considered the KeyWords Plus associated with each paper.
An app to check color balance in indexes for sequencing
Shiny app for exploration of the Genome-wide PeptidoGlycan Profiling dataset of Vibrio cholerae mutant library. Access to this app is password protected while it is under peer review.
The mappings are provided for genes, proteins, metabolites, metabolic reactions, diseases, complexes and publications. This is a REST service for programmatic access to BridgeDb content, provided with interactive Swagger documentation using OpenAPI. For more info see https://www.bridgedb.org/.
Supplemental interactive visualization of Adipose Tissue Gene expression after exercise. Built using flexdashboard.
A tool to predict the risk of experiencing refractory/relapse disease within two years in DLBCL patients treated with R-CHOP.
This Shiny app is used the course CB2030 Systems biology at KTH Royal Instute of Technology.
CellChat's Shiny app which allows interactive exploration of the cell-cell communication that are analyzed by the CellChat R-package
OmicLoupe server. See https://quantitativeproteomics.org/omicloupe/ for info about OmicLoupe.
3D igraph from tsne with variable genes (Data from Tiklova et al. 2016)
Single cell RNA sequencing dataset associated with the manuscript "Amnion signals are essential for mesoderm formation in primates"
scRNA-seq data in: Small molecule screen identifies a salt-inducible kinase inhibitor inducing β-cell proliferation by transiently activating the unfolded protein response
Byrnes, Lauren E., et al. Lineage dynamics of murine pancreatic development at single-cell resolution
The Boreal Rhizospheric Atlas online tool was created to encourage exploration of a metatranscriptomic dataset of Norway spruce fine roots and their associated fungal communities from nutrient limited and nutrient enriched forest plots of the boreal region of Northern Sweden.
Chalmers University of Technology
Fraunhofer Institute for Translational Medicine and Pharmacology
Göteborgs University
KTH Royal Institute of Technology
Karolinska Institutet
Karolinska institutet
LTH Lund University
Linköping University
Lund University
SciLifeLab
Stockholm University
Swedish Meteorological and Hydrological Institute
Swedish University of Agricultural Sciences
Umeå University
University of Helsinki
Uppsala University